杨畅，女，仡佬族，1986年生，博士，教授，贵州医科大学青年博士研究生导师
2004年9月考入华中科技大学，攻读药学本科；2008年6月获得理学学士学位。同年因成绩优异获得本硕连读资格，继续留校攻读硕士学位，并于2010年9月获得硕博连读资格，开始攻读博士学位。2011年9月-2013年3月以联合培养博士研究生身份前往美国德克萨斯州立大学阿灵顿分校纳米物理系学习纳米技术、光热治疗、光动力疗法等。2013年6月毕业于华中科技大学，获理学博士学位。同年9月进入贵州医科大学民族药与中药开发应用教育部工程研究中心从事新型药物传递系统、康复医学与中药新剂型的研究工作，同时在贵州医科大学药学院药剂学教研室承担本科生《药剂学》、《药物制剂设计与研发》以及研究生《现代药剂学》的教学工作；2018年11月-2019年10月获国家留学基金委资助前往英国贝尔法斯特女王大学药学院开展中药新剂型研发的交流学习工作。近五年来，主持国家自然科学技术基金项目2项，省市级科研项目8项（已结题）。已发表研究性论文40余篇，其中以第一作者或通讯作者发表SCI论文20余篇。
研究方向：新型药物传递系统、康复医学与中药新剂型的相关研究。
联系方式：Email:yangchang@gmc.edu.cn
主持的国家自然科学基金项目如下：
1.国家自然科学基金委员会，地区科学基金项目，82360452，基于铁代谢-氧化应激途径介导的低强度经颅磁刺激治疗脑缺血再灌注损伤的作用机制研究，2024-01至2027-12，32万元，在研，主持
2.国家自然科学基金委员会，地区科学基金项目，81860323，利用经颅磁刺激仪构建灯盏乙素磁性纳米递药系统的研究，2019-01至2022-12，35万元，已结题，主持
发表的SCI论文
第一作者发表:
(1)Chang Yang#,*, Shanshan Yang#, Shumei Fang, Lisu Li, Jincheng Jing, Wenting Liu, Cong Wang, Ruixi Li, Yuan Lu,PLGA nanoparticles enhanced cardio-protection of scutellarin and paeoniflorin against isoproterenol-induced myocardial ischemia in rats, International Journal of Pharmaceutics, 2023, 648: 123567, IF: 5.8
(2)Chang Yang#, Qing Zhao#, Shanshan Yang#, Libin Wang, Xingyuan Xu, Lisu Li, and Wafa T. Al-Jamal*,Intravenousadministration ofscutellarinnanoparticlesaugmentstheprotectiveeffect againstcerebralischemia−reperfusioninjuryinrats,MolecularPharmaceutics,2022, 19, 1410−1421, IF: 5.364
(3)Chang Yang, Tao Xia, Changquan Wang, Huiyuan Sun, Yongjun Li, Zipeng Gong, Yueting Li, Lin Zheng*, Yong Huang*, Using the UPLC-ESI-Q-TOF-MSEmethod and intestinal bacteria for metabolite identification in the nonpolysaccharide fraction from Bletilla striata, Biomedical Chromatography, 2019, 33(11): e4637, IF: 1.728
(4)Chang Yang, Lun Ma, Jason Maley, Ramaswami Sammynaiken, Renfei Feng, Guangya Xiang*, Wei Chen*, Photoluminescence and X-ray excited luminescence from glutathione-stabilized gold nanoparticles, Journal of Biomedical Nanotechnology, 2013, 9(11): 1827~1836, IF: 5.256
(5)Chang Yang, Nan Ding, Yibing Xu, Xiaolan Qu, Jing Zhang, Chaoyang Zhao, Liang Hong, Yao Lu, Guangya Xiang*, Folate receptor-targeted quantum dot liposomes as fluorescence probes, Journal of Drug Targeting, 2009, 17(7): 502~511, IF: 2.885
通讯作者发表:
(6)Cong Wang#, Wenting Liu#, Yong Huang, Lin Zheng, Lili Wang, Ruixi Li,Chang Yang*, Mitigating gastrointestinal side effects of risedronate sodium: A study on Bletilla striata polysaccharide microneedle patches, International Journal of Pharmaceutics, 2025, 677: 125609, IF: 5.2
(7)Jincheng Jing#, Shumei Fang#, Yueting Li#, Wenting Liu, Cong Wang, Yanyu Lan, Yonglin Wang*,Chang Yang*,An enhanced cardio-protective effect of nanoparticles loaded with active components from Polygonum orientale L. against isoproterenol-induced myocardial ischemia in rats, International Journal of Pharmaceutics, 2024, :124047, IF: 5.2
(8)Lisu Li#, Jincheng Jing#, Shanshan Yang, Shumei Fang, Wenting Liu, Cong Wang, Ruixi Li, Ting Liu,Lin Zheng,Chang Yang*,Bletilla striatapolysaccharide nanoparticles improved the therapeutic efficacy of omeprazole on the rat gastric ulcer induced by ethanol,MolecularPharmaceutics,2023, 20, 1996-2008,IF: 5.364
(9)Libin Wang#,Shanshan Yang#, Lisu Li, Yong Huang, Ruixi Li, Shumei Fang, Jincheng Jing,Chang Yang*,A low-intensity repetitive transcranial magnetic stimulation coupled to magnetic nanoparticles loaded with scutellarin enhances brain protection against cerebral ischemia reperfusion injury, Journal of Drug Delivery Science and Technology, 2022, 74: 103606, IF: 5.062
(10)Jun Hu, Ashkan Dehsorkhi, Wafa T. Al-Jamal, Yan Zhang, Siying Chen, Chuanyu Yang, Dan Tan, Qing Zhao,Chang Yang*, Yonglin Wang*, Studies on the photothermal effect of PEGylated Fe3O4nanoparticles, Nanoscience and Nanotechnology Letters, 2017, 9(4): 553~558, IF: 1.889
参与发表:
(11)Wei He, Daan Fu, Yongkang Gai, Xingxin Liu,Chang Yang, Zhilan Ye, Xu Chen*,Jia Liu*, Bingcheng Chang*, An infection-microenvironment-targeted and responsive peptide-drug nanosystem for sepsis emergency by suppressing infection and inflammation, Asian Journal of Pharmaceutical Science. 2023, 18(6):100869, IF: 10.2
(12) Jingxuan Guo, Jia Sun, Donghui Liu , Ji Liu, Lijuan Gui, Man Luo, Dexin Kong, Sainaiwaiergul Wusiman,Chang Yang, Ting Liu, Zhenwei Yuan, Ruixi Li, Developing a two-photon "AND" logic probe and its application in Alzheimer's disease differentiation, Analytical Chemistry. 2023, 95(46):16868-16876, IF: 7.4
(13)Ebenezer Addae, Xiuli Dong, Eric McCoy,Chang Yang, Wei Chen, Liju Yang*, Investigation of antimicrobial activity of photothermal therapeutic gold/copper sulfide core/shell nanoparticles to bacterial spores and cells, Journal of Biological Engineering, 2014.6.2, 8: 11, IF: 3.212
(14) Santana Bala Lakshmanan, Xiaoju Zou, Marius Hossu, Lun Ma,Chang Yang, Wei Chen*, Local field enhanced Au/CuS nanocomposites as efficient photothermal transducer agents for cancer treatment, Journal of Biomedical Nanotechnology, 2012.12.01, 8(6): 883~890, IF: 4.216
(15) Yi-Hsuan Tseng, Yuan He, Santana Lakshmanan,Chang Yang, Wei Chen, Long Que*, Optical and thermal response of single-walled carbon nanotube-copper sulfide nanoparticle hybrid nanomaterials, Nanotechnology, 2012.10.22, 23(45): 455708, IF: 3.979
(16) Yao Lu, Nan Ding,Chang Yang, Lei Huang, Jian Liu, Guangya Xiang*, Preparation and in vitro evaluation of a folate-linked liposomal curcumin formulation, Journal of Liposome Research, 2012.2.28, 22(2): 110~119, IF: 1.909
(17) Nan Ding#, Yao Lu#, Robert J Lee#,Chang Yang, Lei Huang, Jian Liu, Guangya Xiang*, Folate receptor-targeted fluorescent paramagnetic bimodal liposomes for tumor imaging, International Journal of Nanomedicine, 2011.10.19, 6(6): 2513~2520, IF: 4.976
(18) Xiaolan Qu,Chang Yang, Jing Zhang, Nan Ding, Yao Lu, Lei Huang, Guangya Xiang*, In vitro evaluation of a Folate-bovine serum albumin-doxorubicin conjugate, Journal of Drug Targeting, 2009.12.9, 18(5): 351~361, IF: 2.491
