
李春,博士,教授,博士生导师、硕士生导师。E-mail: scuchunli@163.com
主要研究方向:手性药物合成与纳米材料制备。
个人简介:2005.9-2014.7就读于四川大学化学学院,分别获得学士学位及博士学位,于2014年9月引进到贵州医科大学药学院药物分析教研室工作,承担本科生《药物分析》、《药物分析实验》,研究生《新药审评与注册》等课程的教学任务。主要研究方向为手性药物合成与纳米材料制备,目前已在Journal of Catalysis,Org. Lett.,ACS Sustainable Chem. Eng.,Org. Chem. Front.,J. Org. Chem.等学术期刊上以第一或通讯作者发表SCI论文28篇,主持国家自然科学基金项目3项,省级项目2项,横向项目1项,申请发明专利7项,授权3项。
代表性项目:
(1)国家自然科学基金,基于金鸡纳碱骨架的手性三齿氮配体的合成及其在酮不对称催化加氢反应中的应用,22262009,主持。
(2)国家自然科学基金,负载型催化剂催化亚胺多相不对称加氢反应研究,21601039,主持。
(3)国家自然科学基金,无机纳米材料担载过渡金属催化杂环芳香酮不对称加氢的性能和机理研究,21562010,主持。
代表性论文:
(1)Zhang L.,ZhouX.,DaiP.,GouW.,WangM.,TianY.,XuY.,*Li C.* Synthesis of Enantiopureβ‑Hydroxy-1,3-dioxolanes by Ir-CatalyzedAsymmetric Hydrogenation ofα‑(1,3-Dioxolane)-ketones, Org. Lett. 2025, 27, 8018−8022;
(2)MengX.,WangY.,TianY.,ZhouY.,ZhouX.,TianW.,Zhang L.;*XuY.,*Li C.* Cinchona-Alkaloid-Derived NNPP Ligands for Iridium-CatalyzedAsymmetric Hydrogenation of Unsymmetrical Benzophenones, Org. Lett. 2025, 27,10797−10801;
(3)Dai P.,Tian Y., Zhou X.,Zhou Y., Tian W., Wang, Y.; ZhangL.,*XuY.,*Li C.* Mn-Catalyzed Asymmetric Transfer Hydrogenation of KetonesImproved by Cinchona Alkaloid-Derived NNS Ligands, J. Org. Chem. 2025, 90, 16993−17004;
(4)Zhang L., Dai P., Meng X., Tian Y., Zhou X., Gou W., Wang Y.,Li C.*Cinchona alkaloids-derived chiral ligands for Mn-catalyzed ATH of ketones: Improvement of enantioselectivity through π-π stacking-induced hydrogen bond,Journal of Catalysis, 2024,439, 115758;
(5)Zhang L.,*Ma N., Wang M., Gou W., Tian J., Xu Q., Zhao C.,Li C.*(o-CF3PhO)3P as a simple coupling reagent for direct amidation via activation of amines, Org. Chem. Front., 2024,11,1796–1803;
(6)Xu Q., Gou W., Dai P., Zhou X., Tian J., Meng X., Tian Y., Zhang L.,*Li C.*Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of β-Keto Ester,J. Org. Chem., 2024,89,1446–1457;
(7)Gou W., Dai P., Wang M., Wang Y., Ma N., Zhou X., Xu Y., Zhang L.,*Li C.* Synthesis of Diverse Ureas from Amines and CO2at Atmospheric Pressure and Room Temperature,J. Org. Chem.,2024, 89, 12498−12507;
(8)Zhang L., Chen Q., Li L., Ma N., Tian J., Sun H., Xu Q., Yang Y.,Li C.*Synthesis of N-Unsubstituted and N3-Substituted Quinazoline-2,4(1H,3H)-diones fromo-Aminobenzamides and CO2at Atmospheric Pressure and Room Temperature,Org. Lett., 2023,25, 2471–2475;
(9)Tian J., Meng X., Sun H., Chen Q., Xu Q., Dai P., Li L., Zhang L.,*Li C.*Cinchona-Alkaloid-Derived NN Ligands and Achiral Phosphines for Iridium-Catalyzed Asymmetric Hydrogenation of Heteroaromatic and α-Chloroheteroaryl Ketones,J. Org. Chem., 2023,88, 9213–9224;
(10)Chen Q., Sun H., Li L., Tian J., Xu Q., Ma N., Li L., Zhang L.,*Li C.*The Ir-Catalyzed Asymmetric Hydrogenation of α-Halogenated Ketones Utilizing Cinchona-Alkaloid-Derived NNP Ligand to Produce (R)- and (S)-Halohydrins,J. Org. Chem., 2022,87, 15986–15997;
(11)Zhang L., Zhang L., Chen Q., Li L., Jiang J., Sun H., Zhao C., Yang Y.,Li C.*Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones,Org. Lett., 2022,24, 415–419;
(12)Zhang L., Chen Q., Li L., Jiang J., Sun H., Li L., Liu T., Zhang L.,*Li C.*Ruthenium-catalyzed asymmetric hydrogenation of aromatic and heteroaromatic ketones using cinchona alkaloid-derived NNP ligands,RSC Advances, 2022,12, 14912–14916;
(13)Zhang L., Jiang J., Li L., Chen Q., Zhang L., Sun H.,Li C.*Sustainable Synthesis of Amides from Carboxylic Acids and Equivalent Amounts of Amines Using a Reusable Brønsted Acidic Ionic Liquid as a Catalyst and a Solvent, ACS Sustainable Chem. Eng., 2022,10, 8433–8442;
(14)Li C., Wang M., Lu X., Zhang L., Jiang J., Zhang L.*Reusable Brønsted Acidic Ionic Liquid Efficiently Catalyzed N-Formylation and N-Acylation of Amines,ACS Sustainable Chem. Eng., 2020,8, 4353–4361.