
个人简介
杨胜钧,博士,副教授,青年硕士/博士生导师。分别于2003年,2010年,2013年在华中师范大学取得学士、硕士、博士学位。博士毕业后先后在中国科学院武汉物理与数学研究所,德国马克斯普朗克生物物理化学研究所,芬兰奥卢大学进行博士后研究。回国后加入海南大学生物医学工程学院。2022年加入贵州医科大学药学院。长期从事小分子探针及磁共振造影剂方面研究。迄今为止已发表16篇SCI论文,其中第一作者身份在包括Angew. Chem. Int. Ed., Anal. Chem.等化学top期刊上发表SCI论文8篇。
学习工作经历
2022.3-至今 贵州医科大学药学院,副教授,青年硕士/博士生导师
2021.6-2022.02 海南大学生物医学工程学院,副教授
2020.2-2020.8 芬兰奥卢大学,博士后
2017.2-2020.1 德国马普生物物理化学研究所,博士后
2014.1-2017.1 中国科学院武汉物理与数学研究所,博士后
2010.9-2013.12 华中师范大学化学学院有机化学专业,博士
2007.9-2010.6 华中师范大学化学学院农药学专业,硕士
主讲课程
主讲本科生《分析化学》课程、参与研究生《新药审评与注册》课程讲授
研究方向
生物标志物(小分子、酶等)特异性探针底物的设计研发及应用
长寿命核自旋单重态造影剂的设计及性能研究
科研情况:
(1)科研项目:
1. 化学(近似)等价的13C双自旋体系的核自旋单重态寿命研究,主持,2023.1-2026.12,国家自然科学基金;
2.氟-19磁共振探针用于细胞内硫醇及其代谢物的检测分析,主持,2022.5-2025.4,贵州医科大学。
(2)代表性科研成果
1. Shengjun Yang#, Philip Saul#, Salvatore Mamone, Lukas Kaltschnee, Stefan Glöggler, Bimodal fluorescence/magnetic resonance molecular probes with extended spin lifetimes, Chem.-Eur. J., DOI: 10.1002/chem.202104158. (中科院二区).
2. Shengjun Yang, Jeffrey McCormick, Salvatore Mamone, Louis-S. Bouchard, Stefan Glöggler, Nuclear Spin Singlet States in Photoactive Molecules: From Fluorescence/NMR Bimodality to a Bimolecular Spin Singlet State Switch, Angew. Chem. Int. Ed., 2019, 58, 2879-2883. (中科院一区)
3. Shengjun Yang, Weiping Jiang, Lili Ren, Yaping Yuan, Bin Zhang, Qing Luo, Qianni Guo, Louis-s. Bouchard, Maili Liu, Xin Zhou, Biothiol Xenon MRI Sensor Based on Thiol-Addition Reaction, Anal. Chem., 2016, 88, 5835-5840. (中科院一区)
4. Shengjun Yang, Qingbin Zeng, Qianni Guo, Shizhen Chen, Hongbin Liu, Maili Liu, M. T. McMahon, Xin Zhou, Detection and differentiation of Cys, Hcy and GSH mixtures by 19F NMR probe, Talanta, 2018, 184, 513-519. (中科院一区)
5. Shengjun Yang, Weiyong Feng, Guoqiang Feng, Development of a near-infrared fluorescent sensor with a large Stokes shift for sensing pyrophosphate in living cells and animals, Anal. Chim. Acta, 2018, 1034, 119-127. (中科院二区)
6. Shengjun Yang, Yaping Yuan, Weiping Jiang, Lili Ren, He Deng, Louis-s. Bouchard, Xin Zhou, Maili Liu, Hyperpolarized 129Xe Magnetic Resonance Imaging Sensor for H2S, Chem.-Eur. J., 2017, 23, 7648-7652. (中科院二区)
(3)会议
1. Shengjun Yang, Jeffrey McCormick, Salvatore Mamone, Louis-S. Bouchard, Stefan Glöggler, Nuclear Spin Singlet States in Photoactive Molecules: From Fluorescence/NMR Bimodality to a Bimolecular Spin Singlet State Switch. ISMAR EUROMAR joint conference, August 2019, Berlin. (Abstract and poster)
2. Shengjun Yang, Jiang Weiping, Luo Qing, Guo Qianni, Zhou Xin, Functionalized Cryptophane-129Xe MRI Biosensor for Biothiols Detection through Thiol-addition Reaction. The 24th International Society for Magnetic Resonance in Medicine (ISMRM). Singapore, May, 2016. (Abstract and talk)
3. Shengjun Yang, Weiping Jiang, Xin Zhou, a novel 129Xe NMR-fluorescence bimodal probe for the detection of hydrogen sulfide. The 16th Beijing Conference and Exhibition on Instrumental Analysis, Beijing, 2015. (Abstract, poster and talk)
欢迎有志于科研的同学报考研究生,欢迎对科研感兴趣的本科生进组学习。
联系方式:yangshengjun@gmc.edu.cn