赵冲-药学院

个人简介

赵冲，博士，副教授，硕导，2020年7月毕业于中国科学院化学研究所，获理学博士学位，2020年9月加入贵州医科大学，药学院（贵州省化学合成药物研发利用工程技术研究中心）青年骨干教师，长期从事药物设计和基于碳材料（富勒烯）的相关研究。以第一作者或通讯作者在Chem. Common., Anal. Chem., ACS Appl. Nano Mater., Chem. Eng. J., Nanoscale等期刊发表研究论文10余篇。截至2024年，主持国家自然科学基金2项，贵州省科技计划1项，中科院协作项目1项，校级项目2项。

（1）研究方向

近年来重点研究方向(欢迎有兴趣的同学报考研究生，也欢迎本科生进组实习)：

1.人工智能应用于药物和材料设计（AI for Drugs & Materials）；

2.碳材料研究：基于富勒烯的超分子光调控及药物分子设计、生物传感、碳材料催化应用等（Carbonmaterialresearch）。

3.生物钾离子/钙离子信号传导研究。

（2）联系方式（邮箱）

zhaoc_chem@126.com

（3）近几年主持科研项目情况

1.光响应偶氮苯-富勒烯超分子系统的可控构筑与性质研究项目编号：52202036资助机构：国家自然科学基金委会；

2.偶氮苯基主体分子可逆调控富勒烯光化学性质及应用研究项目编号：5246020191资助机构：国家自然科学基金委会；

3.富勒烯衍生物与大肠杆菌细胞壁模型及动力学模拟资助机构：中国科学院化学研究所；

4.MOF去除中药提取物中重金属残余新策略研究黔科合基础-ZK[2022]一般402 资助机构：贵州省科学技术厅；

5.MOF-177去除中药提取物中重金属残余的研究校博合J字[2020]061号资助机构：贵州医科大学。

（4）代表性论文、专利情况:

1.Chong Zhao, Guiping Yang, Shu Zhang, Xiao He*, Yeshuang Zhong, and Xiuli Gao*,Enhanced Breathing Effect of Nanoporous UIO-66-DABA Metal−Organic Frameworks with Coordination Defects for High Selectivity and Rapid Adsorption of Hg(II). ACS Appl. Nano Mater. 2023, 6, 19, 18372–18380.

2.Mao Zhang, Xing-Hai Fei, Gui-Ping Yang, Cheng Lin, Wen-Jie Li, Ming-Liang Rao, Meng Zhou,Chong Zhao,* Bin He* and Yong-Long Zhao*, Chiral synthetic unprecedented spiro[indoline-2,3-thiophen]-3-ones via an organocatalytic asymmetric sulfa-Michael/aldol cascade reaction. Organic Chemistry Frontiers. 2024, DOI: 10.1039/d4qo01551g.

3.Gang Yu, Liping Liu,Chong Zhao(共一), Shuaiqi Guo, Haibing Meng, Yongfa Zhu, Xian-Ming Zhang, Enhanced internal electric field of CdS/NU-M Z-scheme heterojunction for efficient photocatalytic hydrogen evolution, Chemical Engineering Journal, 494, 2024, 153099.

4.Guangxing Gu,Chong Zhao(共一), Wei Zhang, Jiajin Weng, Zhenchuang Xu, Jian Wu, Yingbo Xie, Xiao He*, and Yanchuan Zhao*, Chiral Discrimination of Acyclic Secondary Amines by 19F NMR.Anal. Chem. 2024, 96, 2, 730–736.

5.Wei Zhang,Chong Zhao(共一), Wenjie Zhu, Xiao He*, and Yanchuan Zhao*, Conformational Locking as a Strategy to Reverse Ion Recognition Selectivity. 2024,The Journal of Organic Chemistry, accepted, doi:https://doi.org/10.1021/acs.joc.3c02902

6.Zhao Chong; Liu Fuping; Feng Lai; Nie Mingzhe; Lu Yuxi; Zhang Jie; Wang Chunru; Wang Taishan*; Construction of a double-walled carbon nanoring, Nanoscale, 2021, 13(9): 4880-4886.

7.Zhao, Chong; Meng, Haibing; Nie, Mingzhe; Huang, Qiang; Du, Pingwu*; Wang, Chunru*; Wang, Taishan*; Construction of a short metallofullerene-peapod with a spin probe, Chemical Communications, 2019, 55(77): 11511-11514.

8.Ma, Haijun;Zhao, Chong（共同一作）; Meng, Haibing; Li, Ruoxin; Mao, Liucheng; Hu, Danning; Tian, Mei; Yuan, Jinying; Wei, Yen; Multifunctional Organic Fluorescent Probe with Aggregation-Induced Emission Characteristics: Ultrafast Tumor Monitoring, Two-Photon Imaging, and Image-Guide Photodynamic Therapy., ACS Applied Materials & Interfaces, 2021, 13(7): 7987-7996.

9.Zhao, Chong; Tan, Kai; Nie, Mingzhe; Lu, Yuxi; Zhang, Jie; Wang, Chunru; Lu, Xin*; Wang, Taishan*; Scandium Tetrahedron Supported by H Anion and CN Pentaanion inside Fullerene C-80, Inorganic Chemistry, 2020, 59(12): 8284-8290.

10.Zhao, Chong; Nie, Mingzhe; Meng, Haibing; Wang, Chunru*; Wang, Taishan*; Synthesis and Structural Studies of Two Paramagnetic Metallofullerenes with Isomeric C-72 Cage, Inorganic Chemistry, 2019, 58(12): 8162-8168.

11.Zhao, Chong; Meng, Haibing; Nie, Mingzhe; Wang, Xiang; Cai, Zhenfeng; Chen, Ting; Wang, Dong; Wang, Chunru*; Wang, Taishan*; Supramolecular Complexes of C-80-Based Metallofullerenes with [12]Cycloparaphenylene Nanoring and Altered Property in a Confined Space, Journal of Physical Chemistry C, 2019, 123(19): 12514-12520.

12.Zhao Chong; Meng Haibing; Nie Mingzhe; Jiang Li; Wang Chunru; Wang Taishan; Anisotropic Paramagnetic Properties of Metallofullerene Confined in a Metal-Organic Framework, Journal of Physical Chemistry C, 2018, 122(8): 4635-4640.

13.Zhao Chong; Wang Taishan*; Li Yongjian; Meng Haibing; Nie Mingzhe; Tian Jianlei; Wang Chunru*; Awaking N-hyperfine couplings in charged yttrium nitride endohedral fullerenes, Physical Chemistry Chemical Physics, 2017, 19(39): 26846-26850.

14.赵冲;雷丹;陶舒辉;程南璞;甘利华;金属硫化物富勒烯Sc_2S@C_(82)的自下而上C_2增长和异构化,中国科学:化学, 2015, (01): 68-75.

15.Zhao Chong; Lei Dan; Gan Li Hua*; Zhang Zhu Xia; Wang Chun Ru; Theoretical Study on Experimentally Detected Sc2S@C-84, ChemPhysChem, 2014, 15(13): 2780-2784.